Kabozantinib S-malat

Kabozantinib S-malat

CAS NO.:1140909-48-3
Molekulyar formula: C ∝₂ H ∝₀ FN ∝ O ₁₀
Molekulyar og'irligi: 635,6
Purity:>98%

Kabozantinib S-malate|1140909-48-3|Kabozantinib malat|Kabozantinib (S) - malate|Cabometyx|Kabozantinib malat (XL184)|Kabozantinib (S-malat)|XL184|Cometric|UNII-DR7ST46X58|BMS907351|Kabozantinib s-malate [USAN]|Kabozantinib L-malat|DR7ST46X58|CHEBI: 72319
Spetsifikatsiya yoki tozalik 99% dan katta yoki unga teng
Inglizcha nomi Cabozantinib malate (XL184)
Cabozantinib S malatning biokimyoviy mexanizmi (XL184 BMS 907351) 0,035 nM IC50 bilan kuchli VEGFR2 inhibitori, shuningdek, c-Met, Ret, Kit, Flt-1/3/4 inhibitörleri, Tie2 va AXL IC50 1,3 nM, 4 nM, 4,6 nM, 12 nM/11,3 nM/6 nM, 14,3 nM va 7 nM
Saqlash harorati -20 daraja C
Tashish shartlari: ultra past haroratli muz paketini tashish
Harakat inhibitori turi
Ta'sir mexanizmi: gepatotsitlar o'sish omili retseptorlari inhibitori

Kabozantinib malat - IC50 0,035 nM bo'lgan kuchli VEGFR2 inhibitori Cabozantinibning malatidir va shuningdek, IC50 bilan c-Met, Ret, Kit, Flt-1/3/4, Tie2 va AXLni inhibe qiladi. ning 1,3 nM, 4 nM, 4,6 nM, 12 nM/11,3 nM/6 nM, 14,3 nM va 7 nM, mos ravishda
Kabozantinib S-malat VEGFR2, c-Met, Kit, Axl va Flt3 ni inhibe qilish uchun mos ravishda 0,035, 1,3, 4,6, 7 va 11,3 nM IC50 qiymatlari bilan samarali ko'p retseptorli tirozin kinaz inhibitori hisoblanadi.

Ta'minot va spetsifikatsiyalar
Bir nechta spetsifikatsiyalar mavjud va katta miqdorni sozlash mumkin;

Issiq teglar: kabozantinib s-malate, Xitoy kabozantinib s-malate ishlab chiqaruvchilari, etkazib beruvchilari, zavodi